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KMID : 0978920010020040053
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Korean Journal of Clinical Geriatrics
2001 Volume.2 No. 4 p.53 ~ p.66
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Assessment of Cognitive Disorder in Alzheimer’s Disease By the 7 Minute Screen
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Kim In-Seong
Cheon Jin-Sook
Oh Byoung-Hoon
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Abstract
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Background: Alzheimer’s disease is a typical neuropsychiatric disorder with declining of various cognitive function. It may be difficult to differentiated age-associated cognitive decline from mild Alzheimer’s dementia. This study was done to identify cognitive disorders in Alzheimer’s disease using the 7 Minute Screen, The ’7 Minute Screen’ test developed by paul S. Soloman shows high sensitivity and specificity for screening of early Alzheimer’ disease.
Methods: The cognitive deficits were evaluated using the Mini Mental State Examination(MMSE) and the 7 Minute Screen(7 MS) in patients with Alzheimer’s disease(N=28) as well as in age and education level matched healthy controls(N=30). Four individual tests of the 7 MS were consisted of the Benton Temporal Orientation Test, the Memory test, the Clock Drawing and the Category Fluency.
Result: 1. The average scores of four individual tests of the 7 MS for the Alzheimer’s disease were 62.07±40.28 for the Benton Temporal Orientation Test, 8.43±2.36 for the Memory Test, 16.4±2.04 for the Clock Drawing and 8.79±2.36 for the Category Fluency. There were statistically significant differences between test scores of Alzheimer’s disease and controls(p<0.01). 2. Cut-off poimts of individual test scores of the 7 Minute Screen in mild Alzheimer’s disease were 0 for the Benton Temporal Orientation Test, 10 for the Memory Test, 1 for the Clock Drawing and 11 for the Category Fluency. Mild Alzheimer’s disease obtained the scores below these levels. 3. Four individual test scores of the 7 MS seemed to have statistically significant association with MMSE and education level.
Conclusion: Dysfuntion in cognitive areas such as orientation, memory, visuospatial abilities and verbal fluency could be found in mild Alzheimer’s disease. 7 MS to be a valuable tool for the screening of Alzheimer’s disease in the Korean elderly.
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KEYWORD
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Alzheimer’s disease, Neurocognitive deficits, The 7 Minute Screen, MMSE
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